Tucanat 150mg Tucatinib 150mg

Tucatinib is a type of targeted anticancer drug, which is used in combination with other medications for the treatment of advanced breast cancer. Tucatinib belongs to a class of drugs called tyrosine kinase inhibitors. Tucatinib targets HER2 (human epidermal growth factor receptor 2) tyrosine kinase. HER2 receptors are involved in the growth and repair of normal breast cells. But, 10 to 20 percent of breast cancers have a faulty HER2 gene, which makes too many copies of itself. This results in HER2 protein overexpression – too many HER2 receptors on the breast cells – which makes the breast cells grow and divided uncontrollably. Tucatinib works by blocking the activity of HER2, which helps to slow the growth and spread of cancer cells. It is used in combination with trastuzumab and capecitabine because the combination helps patients live longer without their cancer progressing and survive for longer overall.